![]() There were no cases of neonatal herpes and there was no increase in pregnancy-related morbidity among the 94 women who seroconverted. Twenty-one percent of infections occurred in the first trimester, 44 percent in the second trimester, and 35 percent in the third trimester. Thirty-four of the newly infected patients had symptomatic infections. There are two blood tests used to diagnose herpes infections: ELISA test, used for initial testing, detects herpes-specific antibodies. The sensitivity of the DFA method in clinical samples was found to be 61 compared to viral culture. or when the patients partner is infected. Thirty percent acquired the infection in the first trimester, 30 percent in the second trimester, and 40 percent in the third trimester. The turnaround time of this assay was about 6090 min. Polymerase chain reaction assay is the preferred test for confirming HSV in. The results are generally ready in about 10 minutes. Among the 94 women who became seropositive during the prenatal period, 60 had subclinical infections. These tests check blood from a finger stick for antibodies to HSV-2. ![]() After adjustment for a 40-week gestation period, this total represents 2 percent of all susceptible patients. During the course of pregnancy, a total of 94 women became seropositive for HSV. Of the approximately 8,500 women included in the study, 24 percent were HSV-negative at entry into the study 48 percent were seropositive for HSV type 1 antibody 11 percent were seropositive for HSV type 2 antibody and 17 percent were seropositive for both types of antibodies. ![]()
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